Timing of streptococcal serology testing for evidence of preceding Group A streptococcal infection is important. Streptococcal antibodies rise during the first month after infection, plateau for 3-6 months before returning to normal levels at 6-12 months.
Microbiology - Serology
Chilled (2 - 8 degrees Celsius)
If overnight - Chilled (2 - 8 degrees Celsius)
Preferred aliquot serum 2 mL
The cutoff values for serological evidence of Group A streptococcal disease vary dependent on the individual assay used by the laboratory. The reported values may deviate from those stated in the Ministry of Health Rheumatic Fever guideline.
Interpret in conjunction with Anti-Dnase B result.
Reported as International Units per mL:
Normal ASO <200 for adults and <250 for school age children.
ASO DNASE B
<200 IU/ml <200 IU/ml ADULTS
<250 IU/ml <300 IU/ml School Age children
<100 IU/ml <300 U/ml Pre-school children
Latex Turbidimetric Assay
$35.66 (Exclusive of GST)
Onset date of illness desirable.
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