HLA-DQ2/DQ8

Diagnostic Use

IMPORTANT UPDATE: May 2025

HLA DQ2/8 testing is no longer available at Canterbury Health Laboratories.

Please ensure that local Coeliac Disease testing guidelines are updated, as HLA testing recommendations may have changed since pathways were introduced.

Changes to guidelines mean that coeliac disease can be diagnosed in some children without the need for a biopsy.

Coeliac disease can be diagnosed by a paediatric gastroenterologist without a biopsy if both the following are present:
• Anti-tissue transglutaminase (tTG) immunoglobulin A (IgA) more than 10 times the upper limit of normal on 2 different samples
• Positive endomysial antibodies (EMA)

Should your region still recommend testing for HLA DQ2/8 for the exclusion of Coeliac Disease, testing is available through New Zealand Blood Service (NZBS).

New referrals will not be accepted. For new referrals please make direct arrangements with your chosen provider.

Department

Genetics - Molecular Pathology

Delphic Registration Code

MOLP

Synonyms

Coeliac Gene Screen
DQ typing for coeliac disease
HLA-DQ