TNF Biologic Drugs – Adalimumab, Infliximab, and Other non-TNF Biologics

Diagnostic Use

Please indicate which TNF biologic drug the patient is receiving on the request form.
Drug levels of the following TNF Biologics can be measured:
Adalimumab (also known commercial names Amgevita or Humira), Infliximab (Remicade)
Anti-drug antibodies are measured when drug levels are low (<2mg/L)

Other biologic drugs can also be measured as research assays e.g. ustekinumab, vedolizumab, natalizumab. Please indicate the monoclonal antibody drug on the request form and whether anti-drug antibodies or target antigen concentrations are required.

Drug and anti-drug antibodies to Etanercept (Embrel) are not available.

Department

Immunology

Delphic Registration Code

TNF

Laboratory Handling

Phlebotomy

Serum samples should be taken from patients receiving TNF Biologics for at least 10 weeks. Samples should be taken at drug trough, within the 24 hours prior to a dose.

Registration

Register as TNF; Immunology will identify which specific drug to test.

Synonyms

Adalimumab
Amgevita
Humira
Adalimumab antibodies
Infliximab
Remicade
Infliximab antibodies
Ustekinumab - Stelara
Vedolizumab - Entyvio

Turnaround Time

4 weeks