TNF Biologic Drugs – Adalimumab, Infliximab, Ethanercept, Amjevita and Others

Diagnostic Use

Drug levels of the following TNF Biologics can be measured:
Adalimumab (Humira), Infliximab (Remicade) and Ethanercept (Enbrel).
Anti-drug antibodies are measured when drug levels are low.

Other biologic drugs can also be measured e.g. ustekinumab, vedolizumab, natalizumab. Please indicate the monoclonal antibody drug on the request form and whether anti-drug antibodies or target antigen concentrations are required.

Department

Immunology

Delphic Registration Code

TNF

Synonyms

Adalimumab
Adalimumab antibodies
Enbrel = Etanercept
Etanercept
Humira = Adalimumab
Infliximab
Infliximab antibodies
Remicade = Infliximab

Turnaround Time

4 weeks

Specimen Type

• Serum

Specimen Requirements

Tube/Container Type:

Preferred

• Serum (Red Cap)

Acceptable

• SST II (Gold Cap)

Preferred Sample Volume (ml)

4

Paediatric Specimen Requirements

Tube/Container Type:

Preferred

• Serum (Red Cap)

Acceptable

• SST II (Gold Cap)

Preferred Sample Volume (ml)

0.5

Additional Specimen Information

Serum samples should be taken from patients receiving TNF Biologics for at least 10 weeks.
Samples should be taken at drug trough, within the 24 hours prior to a dose.
Please indicate which TNF biologic drug the patient is receiving.

Aliquot Instructions

Sample Type

• Serum

Transport to Lab

Ambient (8 - 24 degrees Celsius)

Additional Referral/Aliquot Information

200uL serum (minimum), 1 mL serum (preferred)

Test Method

Drug levels are measured by ELISA.

anti-drug antibodies are detected by HPLC.

Non-Funded Test Cost

$86.81 (Exclusive of GST)

Billing Code

5851

Additional Costing Information

An additional charge will apply for anti-drug antibody testing.

Contact Information

Enquiry Form