Post-operative monitoring in differentiated thyroid carcinoma (DTC).
Take samples pre or >2 wks post any fine needle aspiration.
Patients who are undergoing biotin therapy and/or ingesting biotin supplements with levels of >100ng/mL will show a falsely low Thyroglobulin result in the Beckman Thyroglobulin assay.
Ambient (8 - 24 degrees Celsius)
If overnight - Frozen
Serum thyroglobulin should be undetectable (<0.1 µg/L) in a patient who has had a total thyroidectomy and has a TSH <0.1 mIU/L.
Anti-thyroglobulin antibodies (TgAb), even at low titre, may interfere with thyroglobulin measurement to cause falsely low or undetectable Tg levels.
There is evidence in patients with DTC that an increase in serum TgAb on serial sampling is a risk factor for disease recurrence.
<0.1 – 58 µg/L in serum
Beckman Coulter Access
$36.97 (Exclusive of GST)
1. Test includes a screen for potentially interfering Tg autoantibodies (TgAb).
2. Serum is the recommended specimen, although serum or lithium heparin plasma may be used for Tg measurement, lithium heparin is not suitable for TgAb test.
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