ETV6::RUNX1 RT-PCR

Diagnostic Use

Test to detect ETV6::RUNX1 transcripts in patients with the t(12;21)(p13;q22)translocation - the most frequent rearrangement found in childhood ALL, occurring in approximately 25% of cases.

Department

Genetics - Molecular Oncology

Delphic Registration Code

MONC

Laboratory Handling

Phlebotomy

3x EDTA (Lavender) dedicated to Genetics

Registration

Send to MONC

Synonyms

ETV6/RUNX1 RT-PCR
ETV6/RUNX1 RT-PCR
t(12;21) RT-PCR
TEL-AML1 RT-PCR

Turnaround Time

7 days

Test Code

3637

Specimen Type

• Whole Blood
• Bone Marrow

Specimen Requirements

Tube/Container Type:

Preferred

• EDTA (Lavender Cap)

Acceptable

• RPMI (Bone Marrow)

Additional Specimen Information

12 ml peripheral blood in EDTA. 1-3 ml of bone marrow in EDTA or RPMI (anticoagulant).
Transport to the laboratory at ambient temperature within 48 hours of collection to ensure high-quality RNA can be extracted.

Aliquot Instructions

Test Method

RNA extraction/storage and nested reverse transcriptase PCR (RT-PCR).

Non-Funded Test Cost

$418.23 (Exclusive of GST)

Billing Code

3637

Additional Costing Information

An additional charge of approximately $200 may be applied to samples received on weekends and public holidays for extraction of RNA by on-call staff.

Contact Information

Enquiry Form