Test to detect TCF3::PBX1 transcripts in patients with the t(1;19)(q23;p13) translocation - about 5-6% of childhood ALL and 3% of adult ALL. It occurs almost exclusively in pre-B-ALL expressing IgM.
Genetics - Molecular Oncology
3x EDTA (Lavender) dedicated to Genetics
Send to MONC
12 ml peripheral blood in EDTA. 1-3 ml of bone marrow in EDTA or RPMI (anticoagulant).
Transport to the laboratory at ambient temperature within 48 hours of collection to ensure high-quality RNA can be extracted.
RNA extraction/storage and nested reverse transcriptase PCR (RT-PCR).
$653.46 (Exclusive of GST)
An additional charge of approximately $200 may be applied to samples received on weekends and public holidays for extraction of RNA by on-call staff.