Cystic fibrosis screening
Book at least 24 hours notice, pref. previous week
By the POP staff
Sweat collected as an in ward procedure
At least 75 mg of sweat, preferably >100 mg
Chloride - mercuric thiocyanate
$179.12 (Exclusive of GST)
Chloride less than 40
A sweat chloride concentration less than 40 mmol/L makes cystic fibrosis unlikely, although cases have been described. The likelihood of cystic fibrosis decreases with decreasing sweat chloride levels so that a sweat chloride less than 20 mmol/L makes cystic fibrosis extremely unlikely."
A sweat chloride concentration between 40 and 60 mmol/L is suggestive of the diagnosis of Cystic Fibrosis. Recommend CFTR mutation analysis to confirm or clarify the diagnosis.
Chloride greater than 60
A sweat chloride concentration greater than 60 mmol/L strongly supports the diagnosis of Cystic Fibrosis. Recommend CFTR mutation analysis to confirm or clarify the diagnosis.