Rivaroxaban, Plasma

Department

Toxicology

Delphic Registration Code

GCQU

Turnaround Time

5 days

Test Code

4678

Specimen Type

• Plasma

Specimen Requirements

Tube/Container Type:

Preferred

• EDTA (Lavender Cap)

Preferred Sample Volume (ml)

4.5

No of Samples Required

1

Paediatric Specimen Requirements

Tube/Container Type:

Preferred

• EDTA (Lavender Cap)

Aliquot Instructions

Sample Type

• Plasma

Transport to Lab

Ambient (8 - 24 degrees Celsius)
If overnight - Chilled (2 - 8 degrees Celsius)

Additional Referral/Aliquot Information

Separate EDTA plasma from red cells and send plasma for analysis. Keep refrigerated.

Interpretation

The standard half-life of rivaroxaban is 7 hours, with time to steady-state of 2 days.

Reference Intervals

For patients taking rivaroxaban 20 mg daily, the expected median trough concentrations is 32 ug/L (5th-95th percentile: 5-155ug/L)

Test Method

LC-MSMS

Non-Funded Test Cost

$110.50 (Exclusive of GST)

Billing Code

4678

Uncertainty of Measurement: Intra- and inter-day coefficients of variation (imprecision) were <10%

Contact Information

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