Anti-Proteinase 3 (PR3) antibodies are primarily associated with ANCA-associated vasculitis, most specifically Granulomatosis with Polyangiitis (GPA).
Presence of antibodies aids diagnosis; patients with known disease use antibody concentrations over time for prognostic indication and may be useful in identification of disease flare and remission.
The clinical relevance of anti-PR3 outside of vasculitis (e.g. inflammatory bowel disease or primary sclerosing polyangiitis) is uncertain.
Anti-PR3, with anti-MPO is automatically reflexed internally from indirect immunofluorescence ANCA testing.
For urgent/rapid testing please telephone the Immunology laboratory.
Please note method change from 27/10/2023; different measurement units apply, quantitative results between methods are NOT comparable.
Immunology
PR3
PR3 Antibodies
PR3-ANCA
PR3
5 days
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