Proteinase 3 antibodies

Diagnostic Use

Anti-Proteinase 3 (PR3) antibodies are primarily associated with ANCA-associated vasculitis, most specifically Granulomatosis with Polyangiitis (GPA).
Presence of antibodies aids diagnosis; patients with known disease use antibody concentrations over time for prognostic indication and may be useful in identification of disease flare and remission.

The clinical relevance of anti-PR3 outside of vasculitis (e.g. inflammatory bowel disease or primary sclerosing polyangiitis) is uncertain.

Anti-PR3, with anti-MPO is automatically reflexed internally from indirect immunofluorescence ANCA testing.

For urgent/rapid testing please telephone the Immunology laboratory.

Please note method change from 27/10/2023; different measurement units apply, quantitative results between methods are NOT comparable.

Department

Immunology

Delphic Registration Code

PR3

Synonyms

PR3 Antibodies
PR3-ANCA
PR3

Turnaround Time

5 days

Test Code

7029