Haematology - Surface Markers
Flow cytometry PNH Screen
PNH Screen flow cytometry
Surface Marker PNH screen
Please indicate if the patient has received RBC transfusion within the previous three months.
Transport to lab room temperature within 48 hours.
Ambient (8 - 24 degrees Celsius)
Minimum aliquot 1 x 5ml EDTA blood. Preferred aliquot 2 x 5ml EDTA blood. Bone Marrow not accepted. Samples must be stored at room temperature and delivered to the laboratory within 48 hours.
Granulocytes are tested for the GPI linked antigen CD24 and FLAER (fluorescent aerolysin – a marker for the GPI anchor). Monocytes are tested for the GPI linked antigen CD14 and FLAER. Red blood cells are tested for the the GPI linked antigen CD59.
Cells negative or weakly positive for GPI linked antigens and/or FLAER indicates the presence of a PNH clone.
Flow Cytometry is the preferred method for PNH testing.
$361.23 (Exclusive of GST)
Samples should be received by lab before 12 noon on Fridays.