Test to determine if a NPM1 mutation is present in the NPM1 gene of AML patients.
This provides prognostic information at diagnosis and can also be used for MRD monitoring.
Note that this assay is not for MRD monitoring.
Genetics - Molecular Oncology
2x EDTA (Lavender) dedicated to Genetics (same sample can be used for FLT3/NPM1/CEBPA testing)
Send to MONC
8 ml peripheral blood in EDTA. 1-3 ml of bone marrow in EDTA or RPMI (anticoagulant).
Send ambient to the laboratory.
NPM1 Negative or Positive.
PCR amplification of the terminal exon (exon 12) of the NPM1 gene, followed by fragment analysis to detect the NPM1 insertion/deletion variants.
NPM1 variants are characterised by Sanger sequencing.
$330.82 (Exclusive of GST)
Urgent tests can be prioritised.
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