NMO is part of the NMOSD (NMO spectrum disorder) together with MOG antibodies.
NMO & MOG antibodies are performed on a dual testing system. Requests for NMO will also have MOG testing performed & reported.
Aquaporin 4 antibodies
Ambient (8 - 24 degrees Celsius)
Indirect immunofluorescence using transfected HEK cell line.
Serum is screened at 1:10
CSF is screened neat.
$245.98 (Exclusive of GST)
Negative NMO-IgG does not exclude the presence of a neuromyelitis optica (NMO)-related disease. NMO-IgG has a sensitivity and specificity of 60-75% and 90-99% respectively for NMO-related diseases (Jacob et al., J Neuroimmunology 187:126-138, 2007)