The MYCN oncogene is amplified in approximately 23% of all neuroblastomas and becomes important for stratification of therapy.
Transport fresh samples at room temperature or 4°C. Frozen tissues kept frozen at -20°C.
10 mL peripheral blood in EDTA. 5 mm cube tissue. Paraffin-embedded tissue or 10 x 10 micron slices.
Note: genetic heterogeneity has been shown in neuroblastomas therefore PCR results should always be interpreted in conjunction with FISH analysis of the MYCN oncogene.
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