The MYCN oncogene is amplified in approximately 23% of all neuroblastomas and becomes important for stratification of therapy.
Department
Genetics
Delphic Registration Code
MONC
Turnaround Time
14 days
Test Code
7096
Specimen Type
Whole Blood
Tissue
Specimen Requirements
Tube/Container Type:
Preferred
EDTA (Lavender Cap)
Acceptable
Pottle
Preferred Sample Volume (ml)
10
Additional Specimen Information
Transport fresh samples at room temperature or 4°C. Frozen tissues kept frozen at -20°C.
Aliquot Instructions
Additional Referral/Aliquot Information
10 mL peripheral blood in EDTA. 5 mm cube tissue. Paraffin-embedded tissue or 10 x 10 micron slices.
Test Method
PCR
Note: genetic heterogeneity has been shown in neuroblastomas therefore PCR results should always be interpreted in conjunction with FISH analysis of the MYCN oncogene.
