Lipoprotein(a) or Lp(a) is a low-density lipoprotein (LDL) particle with an apolipoprotein(a) attached via a disulphide bridge.
The structure of Lp(a) is highly heterogeneous with many different genetically determined apo(a) isoforms. It has strong structural homology with plasminogen and as a result is thought to be pro-thrombotic. It is an independent risk factor for premature coronary artery disease (CAD).
Lp(a) is NOT the same as apolipoprotein A1 which is the protein associated with HDL-cholesterol.
Primary sample should be separated within 4 hours of collection.
Lithium heparin and EDTA plasma are NOT acceptable.
Chilled (2 - 8 degrees Celsius)
If overnight - Frozen
500 ul serum. Store fridge 4°C. Minimum 300 ul serum.
Whilst elevated Lp(a) is an independent CV risk factor, it is not responsive to diet or to mainstream lipid-lowering drugs.
There is no evidence that Lp(a) modification will alter CV risk.
The value in measurement of Lp(a) is when overall CV risk is otherwise borderline and uncertain. In that situation, an elevated Lp(a) may influence the decision towards intervention with statins or other drugs to lower LDL-cholesterol (ie to treat what can be treated).
< 300 mg/L
$15.73 (Exclusive of GST)
"*" indicates required fields