Lipoprotein (a), Serum

Diagnostic Use

Lipoprotein(a) or Lp(a) is a low-density lipoprotein (LDL) particle with an apolipoprotein(a) attached via a disulphide bridge.

The structure of Lp(a) is highly heterogeneous with many different genetically determined apo(a) isoforms. It has strong structural homology with plasminogen and as a result is thought to be pro-thrombotic. It is an independent risk factor for premature coronary artery disease (CAD).

Lp(a) is NOT the same as apolipoprotein A1 which is the protein associated with HDL-cholesterol.

Department

Lipids/Trace Metals

Delphic Registration Code

LPA

Laboratory Handling

Separating

Primary sample should be separated within 4 hours of collection.

Synonyms

Apoprotein (a)

Test Code

4165