Test to detect CBFB::MYH11 transcripts in patients with the t(16;16)(p13;q22) inversion - found in approximately 10% of de novo AML.
Genetics - Molecular Oncology
3x EDTA (Lavender) dedicated to Genetics
Send to MONC
12 ml peripheral blood in EDTA. 1-3 ml of bone marrow in EDTA or RPMI (anticoagulant).
Transport to the laboratory at ambient temperature within 48 hours of collection to ensure high-quality RNA can be extracted.
Reported as positive or negative for CBFB::MYH11 transcripts. If positive, the Type of transcript (i.e. A-J) will be determined.
RNA extraction/storage and nested reverse transcriptase PCR (RT-PCR).
$470.50 (Exclusive of GST)
An additional charge of approximately $200 may be applied to samples received on weekends and public holidays for extraction of RNA by on-call staff.