Indicated for cases with an established diagnosis to guide malignant potential and risk of recurrence.
Normally requested by a specialist endocrinologist.
Note for initial screening purposes, plasma (or urine) metanephrines preferred.
Hereditary paraganglioma-pheochromocytoma (PGL/PCC) syndromes are characterized by paragangliomas (tumors that arise from neuroendocrine tissues distributed along the paravertebral axis from the base of the skull to the pelvis) and pheochromocytomas (paragangliomas that are confined to the adrenal medulla).
See the following link for detailed information regarding the genetics of PGL/PCC syndromes:
https://www.ncbi.nlm.nih.gov/books/NBK1548/
Genetics - Molecular Pathology
MOLP
Paragangliomia
PCC
Phaeochromocytoma
PLG
SDHB
SDHC
SDHD
4 weeks
7302