Hepatitis B is one of the world’s most common infectious diseases. About 350 million people have the virus. Every year between 500,000 to one million people die of HBV-related chronic hepatitis, cirrhosis or liver cancer. Almost 94,000 people have hepatitis B in New Zealand.
Screening for Hepatitis B virus is routinely performed by testing for serologic markers (hepatitis B surface antigen, hepatitis core antigen, hepatitis B surface antibody). Nucleic acid tests for HBV DNA are used as an aid in the management of patients with chronic HBV infection undergoing anti-viral therapy and to measure HBV DNA levels at baseline and during treatment to aid in
assessing response to treatment.
If required, viral resistance genotyping (YMDD mutation analysis) can be added on to a HBV viral load sample if the VL is greater than 1000 IU/mL.
Microbiology - Virology
Dedicated EDTA tubes required, minimum 4mL whole blood
Must not be registered on same request number as CLCR, TVPC, MGTV tests
Please refer to separating guide in Additional Information section below
If sample arrives frozen, please ensure it does not thaw.
HBV viral load
Please refer to separating guidelines in the Additional Information section below.
All unseparated viral loads are required to be received in the laboratory by 4.30pm on Friday
If overnight - Chilled (2 - 8 degrees Celsius)
If separated sample will arrive within 70 hours of collection, chilled transport is acceptable.
If this timeframe cannot be guaranteed, please send samples frozen.
Results are reported as International Units (IU)/mL
Detection and quantitation of Hepatitis B virus (HBV) DNA in human plasma (PCR) : Abbott Alinity m platform.
$284.39 (Exclusive of GST)
The HBV assay is quantitative and provides a measure of the level of HBV replication. It is especially useful in patients with pre-core mutation who may not have detectable HBeAg.
Test Availability - Turnaround times are based on longest expected results received end of week and tested following week. Expect samples received M-Th to have 48 hr turnaround. Testing is performed on Abbott Alinity M platform.
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