Anti glomerular basement membrane antibodies are found in anti-GBM disease (Goodpasture's syndrome). Levels correlate with disease activity and often predict clinical outcome.
Testing may be required urgently together with anti-MPO, anti-PR3. For same day results Mon-Fri, business hours- testing by arrangement only - the Immunology laboratory MUST be telephoned (x89787)
Ambient (8 - 24 degrees Celsius)
Anti glomerular basement membrane antibodies are found in Goodpasture’s syndrome and levels correlate with disease activity and often predict clinical outcome. The autoantibody is directed against the NC1 domain of the α- chain of type IV collagen. Approximately 25% of patients presenting with anti GBM antibodies also present with anti-neutrophil cytoplasmic antibodies, so parallel testing is recommended.
0 – 20 CU
All positives and as required indirect immunofluorescence on primate tissue. Screened at 1 in 10
$45 (Exclusive of GST)
Positive GBM ELISA results will be confirmed by Indirect immunofluorescence on primate kidney.
Batched at least weekly - urgent testing by arrangement
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