Free Light Chains, Serum

Diagnostic Use

The serum free light chains assay is useful in the initial work-up of all plasma cell disorders. An increase in kappa or lambda FLC with an abnormal kappa:lambda ratio can indicate excess monoclonal free light chain production.
FLC assays are useful in monitoring of amyloidosis, light chain myeloma, and non-secretory myeloma and multiple myeloma.
FLC levels change rapidly (half-life is a few hours) compared with intact immunoglobulins (half-life is several weeks) making the FLC assay useful for monitoring the response to chemotherapy or other interventions.


Protein Lab

Delphic Registration Code



Kappa/Lambda Ratio
Light Chains
Serum Free Light Chains

Turnaround Time

3 days

Test Code