FLT3 Kinase Domain Mutation Analysis

Diagnostic Use

Test to determine if there is a mutation in the FLT3 tyrosine kinase domain of the FLT3 gene in AML patients.

NOTE: FLT3 tyrosine kinase domain variants will also be detected on the Myeloid NGS Panel at a sensitivity of 5%. Please refer to the Myeloid NGS Panel in Test Manager for more details and price.

Department

Genetics - Molecular Oncology

Delphic Registration Code

MONC

Laboratory Handling

Phlebotomy

2x EDTA (Lavender) dedicated to Genetics (same sample can be used for FLT3/NPM1/CEBPA)

Registration

Send to MONC

Turnaround Time

7 days

Test Code

8263

Specimen Type

• Whole Blood
• Bone Marrow

Specimen Requirements

Tube/Container Type:

Preferred

• EDTA (Lavender Cap)

Acceptable

• RPMI (Bone Marrow)

Additional Specimen Information

8 ml peripheral blood in EDTA. 1-3 ml of bone marrow in EDTA or RPMI (anticoagulant).
Send ambient to the laboratory.

Aliquot Instructions

Test Method

PCR of the tyrosine kinase domain region of the FLT3 gene followed by EcoRV restriction enzyme digest.

Non-Funded Test Cost

$351.22 (Exclusive of GST)

Billing Code

8263

Contact Information

Enquiry Form