Test to determine if a FLT3-ITD is present in the FLT3 gene of AML patients.
This provides prognostic information at diagnosis.
Genetics - Molecular Oncology
2x EDTA (Lavender) dedicated to Genetics (same sample can be used for FLT3/NPM1/CEBPA testing)
Send to MONC
8 ml peripheral blood in EDTA. 1-3 ml of bone marrow in EDTA or RPMI (anticoagulant).
Send ambient to the laboratory.
FLT-3 ITDs are amplified by PCR using primers flanking exons 14 and 15 of the FLT3 gene. Fragment analysis is used to visualise the PCR products and the ratio of mutant FLT3-ITD /FLT3-wildtype is determined by the height of the fluorescent peaks.
$360.53 (Exclusive of GST)
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