Dihydrotestosterone (DHT) is the most potent naturally occuring androgen in man and is produced throught the action of 5a reductase(s) on testosterone. The 5a reductases are located in skin, hair follicules, prostate, genital skin and liver amongst others. DHT exerts its action via the androgen receptor as does testosterone (T). Both androgens are bound to SHBG.
DHT analysis can be useful in differentiating enzyme defects from androgen receptor defects. In addition DHT levels provide a measure of 5a reductase activity in cases of hisutism and monitoring patients on 5a reductase inhibitors.
5 alpha DHT
If overnight - Frozen
600uL Serum, paediatric absolute minimum 300ul serum. Freeze
Dependent on sex & patient`s age.
|0d to <1w||<0.5 nmol/L|
|1w – <30w||<0.2 nmol/L|
|Female||30w to <10y||<0.2 nmol/L|
|10y to <20y||0.2 – 0.6 nmol/L|
|20y – <110y||<0.7 nmol/L|
|0d to 1w (Premature)||0.3 -1.8 nmol/L|
|0d to 1w (Full term)||0.2 – 2.1 nmol/L|
|Male||1w to <30w||0.4 – 2.9 nmol/L|
|30w to <10y||<0.2 nmol/L|
|10y to <20y||<1.8 nmol/L|
|20y – <110y||2.5 nmol/L|
Liquid Chromatography mass spectrometry (LCMSMS)
$250.00 (Exclusive of GST)
Endocrine and Steroid Laboratory Phone 03 364 0848
For results please contact Canterbury Health Laboratories ph. 03 364 0300.