Dihydrotestosterone, Serum.

Diagnostic Use

Dihydrotestosterone (DHT) is the most potent, naturally occurring androgen in man, responsible for the development and differentiation of male sex characteristics.
DHT is formed when testosterone is reduced by the two isoenzymes of 5-alpha reductase. These are located in the skin, hair follicles, prostate tissue, genital tissue, liver and brain. Like testosterone, DHT exerts its action via the androgen receptor which in turn activates the transcription of various target genes promoting growth.

DHT analysis can be useful in the investigation of 5-alpha reductase deficiency, androgen receptor defects and disorders of sexual development in male infants.
In addition, it can be used for monitoring patients taking 5- alpha reductase inhibitors.

Please be advised DHT is not indicated unless explicitly endorsed by a Chemical Pathologist or Endocrinologist.
Please contact Endolab for further information if required (x80885).

Department

Endo/Steroid Lab

Delphic Registration Code

DHT

Synonyms

5 alpha DHT
DHT
Dihydro T

Turnaround Time

14 days

Test Code

7045

Specimen Type

• Serum

Specimen Requirements

Tube/Container Type:

Preferred

• Serum (Red Cap)

Acceptable

• Serum (Red Cap)

Paediatric Specimen Requirements

Tube/Container Type:

Preferred

• Serum (Red Cap)

Acceptable

• Serum (Red Cap)

Preferred Sample Volume (ml)

0.5

Minimum Sample Volume (ml)

0.3

Pre-testing Requirements

Please be advised, DHT is not indicated unless explicitly endorsed by a Chemical Pathologist or Endocrinologist.
Please contact Endolab for further information if required (x80885).

Aliquot Instructions

Sample Type

• Serum

Minimum Volume (ml)

0.3

Transport to Lab

Frozen
If overnight - Frozen

Additional Referral/Aliquot Information

600uL Serum. Paediatric samples the absolute minimum 300uL of serum. Freeze.

Reference Intervals

Dependent on sex & patient’s age.

Dihydrotestosterone
Sex	Age	Reference Interval
	0d to <1w	<0.5 nmol/L
	1w – <30w	<0.2 nmol/L
Female	30w to <10y	<0.2 nmol/L
	10y to <20y	0.2 – 0.6 nmol/L
	20y – <110y	<0.7 nmol/L
	0d to 1w (Premature)	0.3 -1.8 nmol/L
	0d to 1w (Full term)	0.2 – 2.1 nmol/L
Male	1w to <30w	0.4 – 2.9 nmol/L
	30w to <10y	<0.2 nmol/L
	10y to <20y	<1.8 nmol/L
	20y – <110y	2.5 nmol/L

Test Method

Liquid Chromatography mass spectrometry (LCMSMS)

Non-Funded Test Cost

$267.79 (Exclusive of GST)

Billing Code

7045

Contact Information

Enquiry Form

Contact Information

Enquiry Form