Cystatin C is useful for assessing renal function in patients suspected of having kidney disease, and monitoring treatment response in patients with kidney disease.
Cystatin C is used as a measure of glomerular filtration rate (GFR) in patients where creatinine results may be misleading, such as:
•People with abnormally low or abnormally high muscle mass
Chilled (2 - 8 degrees Celsius)
Cystatin C is freely filtered in the renal glomeruli and is normally re-absorbed in the proximal tubules where it is nearly completely metabolised, leading to insignificant levels in the urine. The proportion of cystatin C found in the serum is inversely proportional to the glomerular filtration rate and is uanaffected by:
Adults Reference interval: 0.62 – 1.11 mg/L
Immunoassay on Siemens BNII nephelometer.
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