Chloride is the most abundant plasma anion. Chloride influences body water distribution in a manner similar to sodium , and is also involved in the maintenance of electrochemical gradients across cell membranes.
In isolation, chloride measurement does not provide much useful clinical information, however it is required in order to calculate the anion gap .
Paediatric Specimen 150 uL in blood gas capillary.
Must arrive in lab within 15 min of collection.
150uL in blood gas capillary or 1.0 mL whole blood in heparinised syringe.
In general, the chloride concentration tracks the sodium concentration. Large discrepancies between sodium and chloride often indicate specimen contamination (for example, contamination with the sodium salt of a drug left in an IV line).
The chloride result is part of the anion gap calculation, which is used to narrow down the causes of a metabolic acidosis. Hyperchloraemia is associated with a normal anion gap metabolic acidosis (i.e. chloride retention to compensate for loss of bicarbonate).
In patients with severe hyperproteinaemia or hyperlipidaemia, blood gas chloride (and sodium) results should be used in preference to those from a laboratory analyser, as laboratory results may be falsely low.
95 – 110 mmol/L
Direct ion specific electrode on a blood gas analyser
$24.50 (Exclusive of GST)
Treat as urgent
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