Tumour marker for medullary thyroid carcinoma (MTC) either sporadic or familial, pre and post op. Not recommended as a screening test for patients because of cost and infrequency of MTC with solitary or dominant thyroid nodules.
collect sample on ice and send direct to lab
register as a chilled sample and send to separating on ice
dedicated aliquot must be made for Calcitonin
If patient is on high dose Biotin therapy (>5 mg/day), wait until at least 8 hours after last dose to take blood sample.
Specimen Collection Protocols:
Place sample tube in water/ slushy ice mixture immediately after blood collection and send to laboratory. Sample is to be separated and aliquoted as soon as possible and the aliquot frozen within 4 hours of collection.
If overnight - Frozen
Freeze within 4 hours of collection
Consult an Endocrinologist or Chemical Pathologist for further information.
<6 months = 0-40 ng/L
6 months -3 years = 0-15 ng/L
3 years – adult (female) = 0-6 ng/L
3 years – adult (male) = 0-10 ng/L
Childhood data from ClinChem 50(10);1828: 2004
Roche immunoelectrochemiluminometric assay (Cobas e411 analyser)
$104.19 (Exclusive of GST)
Uncertainty of Measurement:
18% for > 2.8 ng/L
0.5ng/L < 2.8 ng/L On 9 February 2015 the Calcitonin method and reference interval changed to the Roche method. Results show good agreement with the previous Immulite method from LabPlus, Auckland (send-away test).
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