C-Peptide – urine

Diagnostic Use

May be of value in the assessment of residual pancreatic function in insulin treated diabetics, diagnosis of insulinoma and for investigation for covert insulin administration. It is suggested that an endocrinologist be consulted.

Department

Endocrinology Lab

Delphic Registration Code

CPU

Laboratory Handling

Registration

Send to separating

Separating

Make aliquot for UCRN

Test Adds

24-hour urine stored refrigerated then frozen once collection complete, only stable for 24 h in fridge.

Turnaround Time

7 days

Test Code

7651

Specimen Type

• 24hr Urine

Specimen Requirements

Tube/Container Type:

Preferred

• 24hr Urine Container

Preferred Sample Volume (ml)

500

Additional Specimen Information

24 hour urine collection, no additives.

Aliquot Instructions

Sample Type

• Urine

Minimum Volume (ml)

0.5

Transport to Lab

Chilled (2 - 8 degrees Celsius)
If overnight - Frozen

Additional Referral/Aliquot Information

>0.5 L of 24 hour urine collection. Frozen

West Coast rural sites - Send urine chilled to Greymouth lab. At Greymouth Lab, send urine frozen to CHL.

Interpretation

A deficient plasma C-Peptide response to a defined protein/carbohydrate meal is seen in diabetes mellitus. For most clinical purposes the 24-hr urinary C-Peptide excretion gives an adequate and more convenient index of endogenous pancreatic function. Excessive urinary C-Peptide excretion is seen in insulinoma. Deficient C-Peptide excretion is seen in diabetes mellitus and in hypoglycaemia due to the administration of exogenous insulin.

Reference Intervals

5740 – 60300 pmol/24hr

Test Method

Roche Cobas

Non-Funded Test Cost

$49.61 (Exclusive of GST)

Billing Code

7651

Contact Information

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