Amyloid A

Diagnostic Use

Amyloid A is an acute phase protein, which in response to inflammatory processes exhibits a rapid increase in its blood concentration up to 1000 fold from its initial concentration. Amyloid A is more conclusive than CRP in patients with viral infections, rejection reactions to kidney transplants as well as in patients with cystic fibrosis treated with corticoids. In the case of inflammatory arthritis, Amyloid A was found to exhibit the closest correlation to the activity of the disease.
One particularly important aspect of Amyloid A is that its degradation products can be deposited in various organs as Amyloid A (AA) fibrils, which is a serious complication in chronic inflammatory diseases.

Department

Protein Lab

Delphic Registration Code

AMYA

Turnaround Time

2 weeks

Test Code

5828

Specimen Type

• Serum
• Plasma

Specimen Requirements

Tube/Container Type:

Preferred

• Serum (Red Cap)

Acceptable

• SST II (Gold Cap)
• Lithium Heparin - Non-gel (Green Cap)
• Lithium Heparin - Gel (Light Green Cap)

Preferred Sample Volume (ml)

0.5

Minimum Sample Volume (ml)

0.25

No of Samples Required

1

Additional Specimen Information

Serum is stable for no more than 8 days stored at 2 to 8 degrees C.
Samples can be stored frozen at or below -25 degrees C for up to 3 months if they are frozen within 24 hours after collection.
Avoid repeated freezing/thawing.

Aliquot Instructions

Sample Type

• Serum
• Plasma

Minimum Volume (ml)

0.25

Transport to Lab

Chilled (2 - 8 degrees Celsius)
If overnight - Chilled (2 - 8 degrees Celsius)

Additional Referral/Aliquot Information

Refrigerated if within 5 days of collection, otherwise frozen.

Reference Intervals

< 6.4 mg/L

Measurement uncertainty 12%

Test Method

Quantitation by nephelometric immunoassay on Siemens BNII.

Non-Funded Test Cost

$87.76 (Exclusive of GST)

Billing Code

5828

Contact Information

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