AFP is a plasma protein produced in large amounts by the developing fetus. AFP levels in adults are usually low, however some tumours are known to express AFP.
Indications for testing
Monitoring of tumours known to express AFP (most commonly hepatocellular carcinoma and some germ cell tumours). AFP is NOT recommended for the diagnosis of cancer.
AFP - tumour marker, Serum or Plasma
Tumour Marker - AFP, Serum or Plasma
Ambient delivery to lab
Ambient (8 - 24 degrees Celsius)
If overnight - Chilled (2 - 8 degrees Celsius)
Samples may be stored off the red blood cells if testing is not done completed within 8 hours. Separated specimens are stable for up to 48 hours at 2-8 oC. Outside these timeframes, the separated sample must be stored frozen at -20oC or colder.
In the context of a known AFP-secreting tumour, a rising AFP is consistent with disease progression or recurrence.
Due to its poor specificity, AFP should not be used to diagnose cancer.
Plasma AFP levels will be elevated during pregnancy – the reference interval below relates to non-pregnant individuals only.
0 – 16 ug/L
CMIA Method, Beckman Coulter DxI 800 analyser with Beckman Coulter Access reagents
$25.61 (Exclusive of GST)
If patient is female please specify if test is a tumour marker, or pregnancy related (for fetal neural tube defect).
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