Albumin, Plasma

Diagnostic Use

Albumin is a plasma protein produced by the liver. Albumin is important for the maintenance of plasma oncotic pressure, and is also a transport protein for many circulating molecules, including some drugs.

Albumin is included in the liver function tests panel as a biomarker of hepatic synthetic function. Other circumstances in which plasma albumin may be measured include in the investigation of proteinuria and oedema. Whilst sometimes measured to assess nutritional state, albumin does not perform well as a nutritional biomarker and this practice is therefore discouraged.

Plasma albumin measurement may be used to "correct" another albumin-bound analyte for an abnormal albumin concentration. The most common example is when reporting the albumin-adjusted ("corrected") calcium.

Plasma albumin is included in a number of clinical risk scores such as the Child Pugh score (for hepatic cirrhosis) and the International Staging System for multiple myeloma. Plasma albumin predicts disease progression in patients with chronic kidney disease.


Core Biochemistry

Delphic Registration Code



Alb, plasma

Turnaround Time

3 hours

Test Code