Provides a differential diagnosis of one form of Congenital Adrenal Hyperplasia (CAH) caused by a defect in the 11b hydroxylase enzyme. (see 17a hydroxy progesterone)
11 deoxy cortisol also provides an index of pituitary function when cortisol and 11deoxycortisol are used in conjunction with metapyrone test. 11b hydroxylase is inhibited by metapyrone which results in an increase of cpd S and lowering of cortisol due to the cortisol feed back mechanism on action of ACTH from pituitary. Thus results can help assess pituitary and adrenal functions.
Ambient (8 - 24 degrees Celsius)
Aliquot Instructions - Plasma 250 uL. Freeze/refrigerate
10 – 30 nmol/L
$232.23 (Exclusive of GST)
Uncertainty of Measurement - 3.3 nmol/L; +/- 3 64 nmol/L; +/- 15 (12%) 260nmol/L; +/- 60
For results please contact Canterbury Health Laboratories ph. 03 364 0300.
Steroid Laboratory Phone 03 3640 888
JG Lewis,KHJ Yeo & PA Elder. A competitive Elisa for plasma 11 deoxy cortisol.
Steroids 47:365-372, 1986.