Syphilis serology –Treponema pallidum screening CLIA, Blood

Diagnostic Use

Chemiluminescent immunoassay for syphilis screening

Department

Microbiology - Serology

Delphic Registration Code

SEIA

Synonyms

SEIA
Treponema
Treponemal serology
Syphilis screen

Turnaround Time

4 hours

Specimen Type

• Serum

Specimen Requirements

Tube/Container Type:

Preferred

• Serum (Red Cap)

Preferred if West Coast

• SST II (Gold Cap)

Acceptable

• SST II (Gold Cap)

Preferred Sample Volume (ml)

10

Minimum Sample Volume (ml)

5

No of Samples Required

1

Additional Specimen Information

Pre-Testing Requirements: Onset date of illness desirable.
Do not use specimens; heat inactivated, or grossly haemolysed, cadaver specimens or any other body fluids.
Paediatric specimens: Treponemal specific screening not recommended - Refer additional information below.

Aliquot Instructions

Sample Type

• Serum

Minimum Volume (ml)

0.6

Transport to Lab

Ambient (8 - 24 degrees Celsius)
If overnight - Chilled (2 - 8 degrees Celsius)

Reference Intervals

Refer to Virology/ Serology department  03 3641229  or Microbiologist

Test Method

CLIA method. Diasorin, Liaison XL analyser

Non-Funded Test Cost

$30.17 (Exclusive of GST)

Billing Code

2469

Turnaround Time 3-4 hours on Negative results, positive samples make require additional confirmatory testing.

The interpretation of syphilis in neonates requires specialist input as no single test can be used to diagnose congenital syphilis. Passive transfer of maternal antibodies makes interpretation of neonate serology more complex. Specifically, conducting treponemal tests such as TPHA/TPPA and/or SEIA/CLIA screen testing on neonatal serum is not recommended as passively transferred maternal antibodies can persist for >15 months.

Contact Information

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