Elevated urinary retinol-binding protein may indicate tubular damage which may precede glomerular damage. Plasma retinol-binding protein has been suggested to be a marker of insulin resistance however this is controversial. Circulating levels are associated with nutritional status and it has been reported to be a negative acute phase reactant.
UPP for urine
Testing done only for research after extensive consultation
Patient Specimen Urine 2 mL / plasma 0.5 mL
Chilled (2 - 8 degrees Celsius)
If overnight - Chilled (2 - 8 degrees Celsius)
Contact Canterbury Health Laboratories on +64 3 364 0484 or email LabInfo@cdhb.health.nz
Contact Canterbury Health Laboratories on +64 3 364 0484 or email Labinfo.
Batched for research only
Steroid Laboratory Phone 03 3640 888
For results please contact Canterbury Health Laboratories ph. 03 364 0300.
Lewis JG, Shand BI, Frampton CM & Elder PA. An Elisa for retinol binding protein using monoclonal and polyclonal antibodies: Plasma variation in normal and insulin resistent subjects. Clinical Biochemistry; 40, 828-834, 2007.
Lewis JG, Shand BI, Elder PA & Scott RS. Plasma retinol binding protein is unlikely to be a useful marker of insulin resistence. DIabetes Research & Clinical Practice.; 80 e13-e15.2008.
Lewis JG, Shand BI, Frampton CM, Elder PA & Scott RS. Plasma retinol binding protein is not a marker of insulin resitence in overweight subjects: a three year longitudinal study. Clinical Biochemistry;41 1034-1038, 2008.
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