Fluorescence In Situ Hybridisation (FISH) is a targeted technique, described as a’ hybrid’ of molecular genetic and conventional cytogenetic technologies. FISH can be applied to both cultured and uncultured cells unlike standard cytogenetic techniques which require actively-dividing cells. This means that a variety of specimen types can be processed successfully, even those that conventionally don’t grow well in culture, making FISH a powerful tool for the study of acquired abnormality in bone marrows, tumours and paraffin-embedded specimens.
FISH can determine the copy number of a region of interest and detect specific chromosome and/or and gene rearrangements involving that locus. As a complementary technique, or as a test for targeted abnormalities, FISH has expanded our capabilities for more accurate, rapid and refined cytogenetic diagnoses.
Genetics - Cytogenetics
CTGN
20q12 Deletion - FISH
del (20)(q12) - FISH
FISH, 20q12 Deletion
18 days
7410